Drug Information
Drug General Information | Top | |||
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Drug ID |
D02ZPM
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Former ID |
DIB012993
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Drug Name |
Anpirtoline
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Synonyms |
D-16949
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Drug Type |
Small molecular drug
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Indication | Pain [ICD-11: MG30-MG3Z] | Terminated | [1] | |
Company |
ASTA Medica AG
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Structure |
Download2D MOL |
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Formula |
C10H13ClN2S
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Canonical SMILES |
C1CNCCC1SC2=NC(=CC=C2)Cl
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InChI |
1S/C10H13ClN2S/c11-9-2-1-3-10(13-9)14-8-4-6-12-7-5-8/h1-3,8,12H,4-7H2
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InChIKey |
GGALEXMXDMUMDM-UHFFFAOYSA-N
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CAS Number |
CAS 98330-05-3
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:92968
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Target and Pathway | Top | |||
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Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Modulator | [1] |
5-HT 1B receptor (HTR1B) | Target Info | Modulator | [1] | |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT1 type receptor mediated signaling pathway | ||||
Reactome | Serotonin receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
SIDS Susceptibility Pathways |
References | Top | |||
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REF 1 | Effects of anpirtoline on regional serotonin synthesis in the rat brain: an autoradiographic study. Nucl Med Biol. 2006 Apr;33(3):325-32. |
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