Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03CKF
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| Former ID |
DNC011885
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| Drug Name |
H-Tyr-c[D-Orn-Aic-Glu]-NH2
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| Synonyms |
CHEMBL106849; H-Tyr-c[D-Orn-Aic-Glu]-NH2
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C29H36N6O6
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| Canonical SMILES |
C1CC(C(=O)NC2(CC3=CC=CC=C3C2)C(=O)NC(CCC(=O)NC1)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)N
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| InChI |
1S/C29H36N6O6/c30-21(14-17-7-9-20(36)10-8-17)26(39)33-23-6-3-13-32-24(37)12-11-22(25(31)38)34-28(41)29(35-27(23)40)15-18-4-1-2-5-19(18)16-29/h1-2,4-5,7-10,21-23,36H,3,6,11-16,30H2,(H2,31,38)(H,32,37)(H,33,39)(H,34,41)(H,35,40)/t21-,22+,23-/m0/s1
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| InChIKey |
YFKXNEKIMXIPLT-ZRBLBEILSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor delta (OPRD1) | Target Info | Inhibitor | [1] |
| Opioid receptor mu (MOP) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| cGMP-PKG signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Enkephalin release | ||||
| Opioid proenkephalin pathway | ||||
| Opioid proopiomelanocortin pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | TCR Signaling Pathway | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | ||||
| Opioid Signalling | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Conformational restriction of the phenylalanine residue in a cyclic opioid peptide analogue: effects on receptor selectivity and stereospecificity. J Med Chem. 1991 Oct;34(10):3125-32. | |||
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