Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03DIP
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| Former ID |
DNC014313
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| Drug Name |
3-(2-Diethylamino-propionamino)-rutaecarpine
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| Synonyms |
CHEMBL1098295; 3-(2-Diethylamino-propionamino)-rutaecarpine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C25H27N5O2
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| Canonical SMILES |
CCN(CC)CCC(=O)NC1=CC2=C(C=C1)N=C3C4=C(CCN3C2=O)C5=CC=CC=C5N4
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| InChI |
1S/C25H27N5O2/c1-3-29(4-2)13-12-22(31)26-16-9-10-21-19(15-16)25(32)30-14-11-18-17-7-5-6-8-20(17)27-23(18)24(30)28-21/h5-10,15,27H,3-4,11-14H2,1-2H3,(H,26,31)
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| InChIKey |
XTKDYIOBJOQMHV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
| Cholinesterase (BCHE) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Monoamine Transport | |||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Irinotecan Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors. Eur J Med Chem. 2010 Apr;45(4):1415-23. | |||
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