Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03JYN
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| Former ID |
DNC008483
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| Drug Name |
1-(phenyl(p-tolyl)methylene)thiosemicarbazide
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| Synonyms |
CHEMBL402465; 1-(phenyl(p-tolyl)methylene)thiosemicarbazide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H15N3S
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| Canonical SMILES |
CC1=CC=C(C=C1)C(=NNC(=S)N)C2=CC=CC=C2
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| InChI |
1S/C15H15N3S/c1-11-7-9-13(10-8-11)14(17-18-15(16)19)12-5-3-2-4-6-12/h2-10H,1H3,(H3,16,18,19)/b17-14+
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| InChIKey |
DZOZYORQEZEOCT-SAPNQHFASA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin B (CTSB) | Target Info | Inhibitor | [1] |
| Cathepsin L (CTSL) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Lysosome | |||
| Antigen processing and presentation | ||||
| Phagosome | ||||
| Proteoglycans in cancer | ||||
| Rheumatoid arthritis | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| IL4 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Reactome | Collagen degradation | |||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| Endosomal/Vacuolar pathway | ||||
| Degradation of the extracellular matrix | ||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB. Bioorg Med Chem Lett. 2008 May 1;18(9):2883-5. | |||
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