Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03KLO
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| Former ID |
DNC007127
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| Drug Name |
2,6-dimethyl-8-ethyl-1-deazapurine
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| Synonyms |
133240-06-9; 2-Ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine; 2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine; CHEMBL221579; 3H-Imidazo[4,5-b]pyridine,2-ethyl-5,7-dimethyl-; 5,7-Dimethyl-2-ethylimidazo[4,5-b]pyridine; 3H-Imidazo[4,5-b]pyridine, 2-ethyl-5,7-dimethyl-; 2,6-dimethyl-8-ethyl-1-deazapurine; ACMC-20dzbe; SCHEMBL1918476; CTK4B8431; DTXSID40431137; XWWJWZJOSWSJQV-UHFFFAOYSA-N; ZINC22058897; BDBM50205288; ANW-72022; AKOS000278272; AKOS015904384; RTX-011778; FCH1411209; AM803160; SC-21701; KB-23752; AJ-80864; TC-160767
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H13N3
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| Canonical SMILES |
CCC1=NC2=C(N1)C(=CC(=N2)C)C
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| InChI |
1S/C10H13N3/c1-4-8-12-9-6(2)5-7(3)11-10(9)13-8/h5H,4H2,1-3H3,(H,11,12,13)
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| InChIKey |
XWWJWZJOSWSJQV-UHFFFAOYSA-N
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| CAS Number |
CAS 133240-06-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists. J Med Chem. 2007 Feb 22;50(4):828-34. | |||
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