Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03OGO
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| Former ID |
DNC007148
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| Drug Name |
Cyclosal-d4TMP
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| Synonyms |
CycloSal-d4TMP; cycosal-d4TMP; CHEMBL375767; AC1LABYX; BDBM50206637; 5-methyl-1-[(2R,5S)-5-[(2-oxo-4H-1,3,2; 5-Methyl-1-{5-[(2-oxo(4H-benzo[e]1,3,2-dioxaphosphan-2-yloxy))methyl](2-2,5-dihydrofuryl)}-1,3-dihydropyrimidine-2,4-dione; 5-methyl-1-[(2R,5S)-5-[(2-oxo-4H-1,3,2$l^{5}-benzodioxaphosphinin-2-yl)oxymethyl]-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione; 5-methyl-1-[(2R,5R)-5-(2-oxo-4H-2lambda5-benzo[1,3,2]dioxaphosphinin-2-yloxy)-2,5-dihydro-furan-2-yl]-1H-pyrimidine-2,4-dione
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H17N2O7P
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| Canonical SMILES |
CC1=CN(C(=O)NC1=O)C2C=CC(O2)COP3(=O)OCC4=CC=CC=C4O3
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| InChI |
1S/C17H17N2O7P/c1-11-8-19(17(21)18-16(11)20)15-7-6-13(25-15)10-24-27(22)23-9-12-4-2-3-5-14(12)26-27/h2-8,13,15H,9-10H2,1H3,(H,18,20,21)/t13-,15+,27?/m0/s1
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| InChIKey |
NEUXRWCLDPVEMR-OHDXJBIGSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| WikiPathways | Irinotecan Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides. J Med Chem. 2007 Mar 22;50(6):1335-46. | |||
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