Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03SHD
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| Former ID |
DNC000974
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| Drug Name |
Myo-inositol
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| Synonyms |
Scyllo-inositol; inositol; Muco-Inositol; epi-Inositol; i-Inositol; meso-Inositol; Allo-inositol; 87-89-8; 1D-Chiro-inositol; 1L-Chiro-inositol; 488-59-5; Scyllitol; 643-12-9; D-(+)-chiro-Inositol; cis-Inositol; mesoinositol; Quercinitol; Myoinosite; Dambose; Cyclohexane-1,2,3,4,5,6-hexaol; Neo-inositol; Meat sugar; 6917-35-7; Phaseomannite; Inositina; Cocositol; D-chiro-Inositol; Inositene; Inosital; Iso-inositol; cyclohexane-1,2,3,4,5,6-hexol; Phaseomannitol; Cyclohexitol; Mesoinosit; Scyllite; Mesoinosite; Inosite
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| Drug Type |
Small molecular drug
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| Indication | Alzheimer disease [ICD-11: 8A20; ICD-10: G30, G30.9; ICD-9: 331] | Phase 2 | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C6H12O6
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| Canonical SMILES |
C1(C(C(C(C(C1O)O)O)O)O)O
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| InChI |
1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H
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| InChIKey |
CDAISMWEOUEBRE-UHFFFAOYSA-N
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| CAS Number |
CAS 551-72-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
2958, 3437, 8408, 8409, 73813, 86405, 99187, 105284, 105285, 105291, 405648, 419053, 474354, 594439, 594440, 606061, 820280, 822652, 841533, 3133547, 3155010, 3155011, 6332601, 7888419, 8137917, 8138252, 8138293, 8138294, 8141702, 8145718, 8146839, 8146881, 8150849, 10523934, 10523935, 10523936, 10531552, 10537350, 10548140, 11364489, 11367051, 11369613, 11371925, 11375023, 11377775, 11446130, 11455636, 11490868, 11493007, 11495409
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| ChEBI ID |
CHEBI:17268
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| SuperDrug ATC ID |
A11HA07
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| SuperDrug CAS ID |
cas=006556112
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Amyloid beta A4 protein (APP) | Target Info | Inhibitor | [1] |
| Mycobacterium CDP-diacylglycerol-inositol phosphatidyltransferase (MycB pssA) | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Notch signaling pathway | |||
| Alzheimer's disease | ||||
| Reactome | Nuclear signaling by ERBB4 | |||
| Degradation of the extracellular matrix | ||||
| Regulated proteolysis of p75NTR | ||||
| NRIF signals cell death from the nucleus | ||||
| Activated NOTCH1 Transmits Signal to the Nucleus | ||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
| EPH-ephrin mediated repulsion of cells | ||||
| WikiPathways | Notch Signaling Pathway | |||
| Signaling by ERBB4 | ||||
| Signaling by NOTCH3 | ||||
| Signaling by NOTCH4 | ||||
| Signaling by NOTCH1 | ||||
| Signaling by NOTCH2 | ||||
| Notch Signaling Pathway | ||||
| Alzheimers Disease | ||||
| Signalling by NGF | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | Phosphatidylinositol synthesis in mycobacteria. Biochim Biophys Acta. 1999 Jan 4;1436(3):437-50. | |||
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