Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03UTI
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| Former ID |
DNC013441
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| Drug Name |
4-iodo-1H-indazole
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| Synonyms |
4-iodo-1H-indazole; 885522-11-2; 4-Iodoindazole; 4-IODO (1H)INDAZOLE; CHEMBL246534; zlchem 1146; PubChem21944; SCHEMBL358061; 4-Iodo-1H-indazole, 95%; 4-IODO-(1H)-iNDAZOLE; 1H-INDAZOLE, 4-IODO-; CTK8B7170; ZLD0614; DTXSID10646276; MolPort-009-197-588; CJQXSPSUIGJNJX-UHFFFAOYSA-N; ZX-RL006042; BCP26449; ZINC14983484; BDBM50209235; ANW-56585; CI-483; AKOS015853740; FCH1325887; VI20042; QC-2871; PB27826; RP05951; AS-50534; AJ-65949; EN002531; KB-39256; OR308061; AK-27887; TC-062829; DB-023141; AB0037276; ST1100625; AX8158792; Y4536; AM20041322
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C7H5IN2
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| Canonical SMILES |
C1=CC2=C(C=NN2)C(=C1)I
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| InChI |
1S/C7H5IN2/c8-6-2-1-3-7-5(6)4-9-10-7/h1-4H,(H,9,10)
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| InChIKey |
CJQXSPSUIGJNJX-UHFFFAOYSA-N
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| CAS Number |
CAS 885522-11-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. | |||
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