Drug Information
Drug General Information | Top | |||
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Drug ID |
D03YOS
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Former ID |
DCL000196
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Drug Name |
Phenoxodiol
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Synonyms |
Dehydroequol; Idronoxil; Haginin E; NV 06; NV-06; Idronoxil (USAN/INN); 2H-1-benzopyran-7-0,1,3-(4-hydroxyphenyl); 3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol; 3-(4-Hydroxyphenyl)-2H-chromen-7-ol; 7-hydroxy-3-hydroxyphenyl-1H-benzopyran
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Drug Type |
Small molecular drug
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Indication | Ovarian cancer [ICD-11: 2C73; ICD-10: C56] | Phase 1/2 | [1] | |
Therapeutic Class |
Anticancer Agents
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Company |
Marshall Edwards
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Structure |
Download2D MOL |
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Formula |
C15H12O3
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Canonical SMILES |
C1C(=CC2=C(O1)C=C(C=C2)O)C3=CC=C(C=C3)O
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InChI |
1S/C15H12O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-8,16-17H,9H2
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InChIKey |
ZZUBHVMHNVYXRR-UHFFFAOYSA-N
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CAS Number |
CAS 81267-65-4
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PubChem Compound ID | ||||
PubChem Substance ID |
3191506, 9374282, 15121904, 30422461, 47206346, 50066225, 52830969, 53789188, 57304385, 57399844, 68529941, 99299658, 113468599, 119525774, 126598392, 126684168, 134338864, 135142360, 136341474, 136929242, 137248187, 140343573, 152057424, 162248991, 162916982, 163368956, 164787401, 172912681, 174006673, 175426901, 176238356, 184603132, 186024306, 198937807, 221678827, 223509024, 223535513, 223682224, 223704958, 224588223, 226515077, 243323551, 249727332, 249780348, 252303380
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References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT00382811) OVATURE (OVArian TUmor REsponse) A Phase III Study of Weekly Carboplatin With and Without Phenoxodiol in Patients With Platinum-Resistant, Recurrent Epithelial Ovarian Cancer. U.S. National Institutes of Health. | |||
REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. |
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