Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04ALU
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| Former ID |
DIB018208
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| Drug Name |
[3H](+)-cis-diltiazem
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| Synonyms |
[3H]-(+)-cis-diltiazem
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C22H26N2O4S
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| Canonical SMILES |
CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
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| InChI |
1S/C22H26N2O4S/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3/h5-12,20-21H,13-14H2,1-4H3
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| InChIKey |
HSUGRBWQSSZJOP-UHFFFAOYSA-N
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| CAS Number |
CAS 34933-06-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4556838, 8151955, 10522522, 10589367, 11335179, 11360418, 11363138, 11365700, 11368262, 11374982, 11376424, 11461390, 11485548, 11489552, 11493076, 11494058, 14879942, 29222221, 47476379, 47550480, 47846442, 47995763, 50100216, 50100217, 50855580, 85245799, 85789652, 88977023, 103094892, 103154421, 104011325, 104302456, 104829104, 117600280, 118491175, 124960914, 125350387, 128108067, 135049062, 135265001, 135651160, 142577305, 143684696, 144239374, 162873103, 164808988, 174006614, 179039636, 184530473, 221672747
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| ChEBI ID |
CHEBI:82814
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2512). | |||
| REF 2 | High-affinity binding of DTZ323, a novel derivative of diltiazem, to rabbit skeletal muscle L-type Ca++ channels. J Pharmacol Exp Ther. 1997 Apr;281(1):173-9. | |||
| REF 3 | SR 33557, a novel calcium entry blocker. II. Interactions with 1,4-dihydropyridine, phenylalkylamine and benzothiazepine binding sites in rat heart sarcolemmal membranes. J Pharmacol Exp Ther. 1990 Nov;255(2):600-7. | |||
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