Drug Information
Drug General Information | Top | |||
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Drug ID |
D04HBL
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Drug Name |
PMID30107136-Compound-Example59
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Drug Type |
Small molecule immunotherapy
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Indication | Hepatitis [ICD-11: DB97.Z] | Patented | [1] | |
Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Patented | [1] | ||
Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] | Patented | [1] | ||
Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
Company |
RIJKSUNIVERSITEIT GRONINGEN
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Structure |
Download2D MOL |
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Formula |
C35H33N5O3
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Canonical SMILES |
C1COCCN1CCNCC2=C(N=C(O2)COC3=NC=CC(=C3C#N)C4=CC=CC=C4)C5=CC=C(C=C5)C6=CC=CC=C6
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InChI |
1S/C35H33N5O3/c36-23-31-30(28-9-5-2-6-10-28)15-16-38-35(31)42-25-33-39-34(29-13-11-27(12-14-29)26-7-3-1-4-8-26)32(43-33)24-37-17-18-40-19-21-41-22-20-40/h1-16,37H,17-22,24-25H2
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InChIKey |
LEMZNPCBMGJIOU-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target Info | Inhibitor | [1] |
Target's Patent Info | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target's Patent Info | [1] |
References | Top | |||
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REF 1 | A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678. |
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