Drug Information
Drug General Information | Top | |||
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Drug ID |
D04ISG
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Former ID |
DNC005723
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Drug Name |
3-(1-Chloro-7-methoxy-naphthalen-2-yl)-pyridine
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Synonyms |
SCHEMBL4517614; BDBM8913; CHEMBL371430; Pyridine-substituted naphthalene 14; ZINC13674470; 3-(1-chloro-7-methoxy-2-naphthyl)pyridine; 3-(1-chloro-7-methoxynaphthalen-2-yl)pyridine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H12ClNO
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Canonical SMILES |
COC1=CC2=C(C=C1)C=CC(=C2Cl)C3=CN=CC=C3
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InChI |
1S/C16H12ClNO/c1-19-13-6-4-11-5-7-14(16(17)15(11)9-13)12-3-2-8-18-10-12/h2-10H,1H3
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InChIKey |
KRLGQBXIHBDUPS-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] | |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Androgen biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
Prolactin signaling pathway | ||||
Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
Steroidogenesis | ||||
Reactome | Androgen biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Steroid Biosynthesis | ||||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Glucocorticoid & Mineralcorticoid Metabolism | ||||
Prostate Cancer | ||||
Phase 1 - Functionalization of compounds | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart fa... J Med Chem. 2005 Oct 20;48(21):6632-42. |
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