Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04JGC
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| Former ID |
DNC007434
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| Drug Name |
(R,R)-(-)-fenoterol
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| Synonyms |
UNII-5Z64M7W0JM; CHEMBL388570; 5Z64M7W0JM; R,R-Fenoterol; Fenoterol, R,R'-; Men 1191; Fenoterol [MI]; Fenoterol [INN]; (R,R)-Fenoterol; Fenoterol [USAN]; Fenoterol [VANDF]; Fenoterol [MART.]; (R,R')-Fenoterol; Fenoterol [WHO-DD]; AC1LEM52; 69421-37-0; SCHEMBL249376; ZINC57320; BDBM50213098; 130156-24-0; UNII-22M9P70OQ9 component LSLYOANBFKQKPT-DIFFPNOSSA-N; 5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]benzene-1,3-diol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H21NO4
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| Canonical SMILES |
CC(CC1=CC=C(C=C1)O)NCC(C2=CC(=CC(=C2)O)O)O
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| InChI |
1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17+/m1/s1
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| InChIKey |
LSLYOANBFKQKPT-DIFFPNOSSA-N
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| CAS Number |
CAS 69421-37-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor beta-1 (ADRB1) | Target Info | Inhibitor | [1] |
| Adrenergic receptor beta-2 (ADRB2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Endocytosis | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Salivary secretion | ||||
| Gap junction | ||||
| Dilated cardiomyopathy | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Beta2 adrenergic receptor signaling pathway | ||||
| Beta1 adrenergic receptor signaling pathway | ||||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Pathway Interaction Database | Arf6 trafficking events | |||
| Arf6 signaling events | ||||
| Reactome | Adrenoceptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Vitamin D Receptor Pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| Endothelin Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor. J Med Chem. 2007 Jun 14;50(12):2903-15. | |||
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