Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04KUP
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| Former ID |
DNC013440
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| Drug Name |
6-bromo-1H-indazole
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| Synonyms |
6-bromo-1H-indazole; 79762-54-2; 6-Bromoindazole; 6-Bromo-2H-indazole; 1H-Indazole, 6-bromo-; CHEMBL247365; 1H-INDAZOLE,6-BROMO-; 1788080-23-8; 6-Bromo-1H-indazole, 97%; 6- Bromoindazole; PubChem7831; zlchem 1237; 6-broMo-1H indazole; 6-bromo-1-H-indazole; 6-bromanyl-1H-indazole; ACMC-209pi5; SCHEMBL5902; KSC376S4P; 6-Bromo-1H-indazole, 95%; AMBZ0200; AC1Q251Y; CTK2H6947; ZLE0012; DTXSID80591229; MolPort-029-084-056; WMKDUJVLNZANRN-UHFFFAOYSA-N; MolPort-000-001-819; ZINC8764137; KS-000002SJ; CS-D0757; BCP00386; ACN-S003161; ACT06505
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H5BrN2
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| Canonical SMILES |
C1=CC2=C(C=C1Br)NN=C2
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| InChI |
1S/C7H5BrN2/c8-6-2-1-5-4-9-10-7(5)3-6/h1-4H,(H,9,10)
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| InChIKey |
WMKDUJVLNZANRN-UHFFFAOYSA-N
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| CAS Number |
CAS 79762-54-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. | |||
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