Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04QAD
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| Former ID |
DNC012419
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| Drug Name |
4-tert-Butyl-N-(4-phenyl-thiazol-2-yl)-benzamide
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| Synonyms |
4-tert-Butyl-N-(4-phenyl-thiazol-2-yl)-benzamide; CHEMBL293635; 4-tert-butyl-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; BAS 03572060; AC1Q1LYP; AC1LGN92; Oprea1_621031; Oprea1_258896; MolPort-001-030-330; ZINC342768; BDBM50101785; STK401915; AKOS000569708; MCULE-2080665457; ST50017828; N-(4-Phenyl-2-thiazolyl)-4-tert-butylbenzamide; AG-690/09665053
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H20N2OS
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| Canonical SMILES |
CC(C)(C)C1=CC=C(C=C1)C(=O)NC2=NC(=CS2)C3=CC=CC=C3
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| InChI |
1S/C20H20N2OS/c1-20(2,3)16-11-9-15(10-12-16)18(23)22-19-21-17(13-24-19)14-7-5-4-6-8-14/h4-13H,1-3H3,(H,21,22,23)
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| InChIKey |
JXOGYJOCFUSOPS-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9. | |||
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