Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04QXM
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| Former ID |
DNC012689
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| Drug Name |
Tyr-D-Ala-Phe-Asp-Val-Val-Thr[Beta-D-Glc]-Gly-NH2
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
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| Formula |
C47H69N9O17
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| Canonical SMILES |
CC(C)C(C(=O)NC(C(C)C)C(=O)NC(C(C)OC1C(C(C(C(O1)CO)O)O)O)C(=O)NCC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(CC3=CC=C(C=C3)O)N
|
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| InChI |
1S/C47H69N9O17/c1-21(2)34(45(70)55-35(22(3)4)46(71)56-36(44(69)50-19-32(49)59)24(6)72-47-39(64)38(63)37(62)31(20-57)73-47)54-43(68)30(18-33(60)61)53-42(67)29(17-25-10-8-7-9-11-25)52-40(65)23(5)51-41(66)28(48)16-26-12-14-27(58)15-13-26/h7-15,21-24,28-31,34-39,47,57-58,62-64H,16-20,48H2,1-6H3,(H2,49,59)(H,50,69)(H,51,66)(H,52,65)(H,53,67)(H,54,68)(H,55,70)(H,56,71)(H,60,61)/t23-,24-,28+,29+,30+,31-,34+,35+,36+,37-,38+,39-,47+/m1/s1
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| InChIKey |
QTEVIWGWCOWBNP-CNGXOXJSSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor delta (OPRD1) | Target Info | Inhibitor | [1] |
| Opioid receptor mu (MOP) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| cGMP-PKG signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Enkephalin release | ||||
| Opioid proenkephalin pathway | ||||
| Opioid proopiomelanocortin pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | TCR Signaling Pathway | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | ||||
| Opioid Signalling | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides. J Med Chem. 1997 Aug 29;40(18):2948-52. | |||
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