Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04SYM
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| Former ID |
DNC008951
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| Drug Name |
Isosorbide-2-(methylcarbamate)-5-mononitrate
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| Synonyms |
CHEMBL492179; Isosorbide-2-(methylcarbamate)-5-mononitrate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H12N2O7
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| Canonical SMILES |
CNC(=O)OC1COC2C1OCC2O[N+](=O)[O-]
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| InChI |
1S/C8H12N2O7/c1-9-8(11)16-4-2-14-7-5(17-10(12)13)3-15-6(4)7/h4-7H,2-3H2,1H3,(H,9,11)/t4-,5+,6+,7+/m0/s1
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| InChIKey |
DEDWFQACIHPQHF-BDVNFPICSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetylcholinesterase (AChE) | Target Info | Inhibitor | [1] |
| Cholinesterase (BCHE) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Cholinergic synapse | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| WikiPathways | Irinotecan Pathway | |||
| Monoamine Transport | ||||
| Biogenic Amine Synthesis | ||||
| Acetylcholine Synthesis | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Isosorbide-2-carbamate esters: potent and selective butyrylcholinesterase inhibitors. J Med Chem. 2008 Oct 23;51(20):6400-9. | |||
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