Drug Information
Drug General Information | Top | |||
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Drug ID |
D04UJI
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Former ID |
DNC011660
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Drug Name |
Naphthalene-2-carboxylic acid hydroxyamide
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Synonyms |
2-Naphthohydroximic acid; 2-Naphthylhydroxamic acid; N,N-Naphthaloylhydroxylamine; 2-NAPHTHOHYDROXAMIC ACID; 10335-79-2; 2-Naphthoylhydroxamic acid; 2-Naphthalenecarboxamide, N-hydroxy-; N-Hydroxy-2-naphthalenecarboxamide; Naphthalene-2-carboxylic acid hydroxyamide; CHEMBL156672; N-hydroxynaphthalene-2-carboxamide; SCHEMBL6010034; AC1L18K7; DTXSID70145795; KUC110312N; BDBM50015160; AKOS000178377; KSC-264-28-1; LS-95339; 2-Naphthalenecarboxamide, N-hydroxy- (9CI)
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C11H9NO2
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Canonical SMILES |
C1=CC=C2C=C(C=CC2=C1)C(=O)NO
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InChI |
1S/C11H9NO2/c13-11(12-14)10-6-5-8-3-1-2-4-9(8)7-10/h1-7,14H,(H,12,13)
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InChIKey |
PCJLUGWQCHMMAG-UHFFFAOYSA-N
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CAS Number |
CAS 10335-79-2
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
Resolvin D biosynthesis | ||||
Leukotriene biosynthesis | ||||
Lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | ||||
Aspirin triggered resolvin E biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Ovarian steroidogenesis | ||||
Toxoplasmosis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Vitamin D Receptor Pathway | |||
Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships. J Med Chem. 1990 Mar;33(3):992-8. |
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