Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05DAF
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| Former ID |
DNC006792
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| Drug Name |
N-(3-aminophenyl)benzenesulfonamide
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| Synonyms |
N-(3-aminophenyl)benzenesulfonamide; 104997-09-3; Benzenesulfonamide, N-(3-aminophenyl)-; CHEMBL378618; ACMC-20f7rf; 3-phenylsulfonamidoaniline; AC1Q51QH; 3-benzenesulfonylaminoaniline; SCHEMBL2723618; CTK0G5849; DTXSID40474387; MolPort-004-296-827; RUYQFOIEMVGGQT-UHFFFAOYSA-N; ZINC22145186; BDBM50193461; AKOS000132984; NE22031; ACN-049935; MCULE-1854488236; EN300-40178; A839866
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C12H12N2O2S
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| Canonical SMILES |
C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)N
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| InChI |
1S/C12H12N2O2S/c13-10-5-4-6-11(9-10)14-17(15,16)12-7-2-1-3-8-12/h1-9,14H,13H2
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| InChIKey |
RUYQFOIEMVGGQT-UHFFFAOYSA-N
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| CAS Number |
CAS 104997-09-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 6 receptor (HTR6) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | |||
| Reactome | Serotonin receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors. J Med Chem. 2006 Aug 24;49(17):5217-25. | |||
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