Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05HBF
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| Former ID |
DNC011391
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| Drug Name |
6,7-Dihydroxy-2-phenyl-chromen-4-one
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| Synonyms |
6,7-dihydroxyflavone; 38183-04-9; 6,7-dihydroxy-2-phenyl-4H-chromen-4-one; 6,7-Dihydroxy-2-phenyl-chromen-4-one; 6,7-dihydroxy flavone; 4H-1-Benzopyran-4-one, 6,7-dihydroxy-2-phenyl-; CHEMBL300814; 6,7-dihydroxy-2-phenylchromen-4-one; SR-05000002250; PubChem9843; 6,7 - Dihydroxyflavone; AC1NS43N; SPECTRUM1500718; SCHEMBL980197; DivK1c_000421; CTK4H9455; KBio1_000421; HMS501F03; DTXSID60191569; NINDS_000421; GSAOUZGPXSGVRS-UHFFFAOYSA-N; ZINC3871176; BDBM50077318; AKOS024283483; CCG-208431; MCULE-6698063887; IDI1_000421; ACM38183049
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H10O4
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=O)C3=CC(=C(C=C3O2)O)O
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| InChI |
1S/C15H10O4/c16-11-7-14(9-4-2-1-3-5-9)19-15-8-13(18)12(17)6-10(11)15/h1-8,17-18H
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| InChIKey |
GSAOUZGPXSGVRS-UHFFFAOYSA-N
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| CAS Number |
CAS 38183-04-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aldose reductase (AKR1B1) | Target Info | Inhibitor | [1] |
| BioCyc | Methylglyoxal degradation III | |||
| Acetone degradation I (to methylglyoxal) | ||||
| KEGG Pathway | Pentose and glucuronate interconversions | |||
| Fructose and mannose metabolism | ||||
| Galactose metabolism | ||||
| Glycerolipid metabolism | ||||
| Metabolic pathways | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathwhiz Pathway | Fructose and Mannose Degradation | |||
| Pyruvate Metabolism | ||||
| Pterine Biosynthesis | ||||
| Glycerolipid Metabolism | ||||
| Galactose Metabolism | ||||
| WikiPathways | Metapathway biotransformation | |||
| Polyol Pathway | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-Benzopyran-4-one antioxidants as aldose reductase inhibitors. J Med Chem. 1999 Jun 3;42(11):1881-93. | |||
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