Drug Information
Drug General Information | Top | |||
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Drug ID |
D05NQX
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Drug Name |
PD-152255
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Synonyms |
164917-23-1
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C46H54N6O2
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Canonical SMILES |
C1CCN(CC1)CCCOC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC=CCN5C6=CC=CC=C6N=C5C7=CC=C(C=C7)OCCCN8CCCCC8
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InChI |
1S/C46H54N6O2/c1-7-27-49(28-8-1)31-13-35-53-39-23-19-37(20-24-39)45-47-41-15-3-5-17-43(41)51(45)33-11-12-34-52-44-18-6-4-16-42(44)48-46(52)38-21-25-40(26-22-38)54-36-14-32-50-29-9-2-10-30-50/h3-6,11-12,15-26H,1-2,7-10,13-14,27-36H2/b12-11+
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InChIKey |
RTRBUDIKCGJLKP-VAWYXSNFSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Dopamine D3 receptor (D3R) | Target Info | Modulator | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Dopaminergic synapse | ||||
Reactome | Dopamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Nicotine Activity on Dopaminergic Neurons | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Pharmacological characterization of PD 152255, a novel dimeric benzimidazole dopamine D3 antagonist. Pharmacol Biochem Behav. 1998 Feb;59(2):487-93. |
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