Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05OUY
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| Former ID |
DNC005387
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| Drug Name |
(R)-2-(4-Isobutyl-phenyl)-propionamide
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| Synonyms |
UNII-LMA883899Q; LMA883899Q; 121839-78-9; (R)-Ibuprofenamide; (-)-Ibuprofenamide; Ibuprofenamide, (R)-; (R)-2-(4-(Isobutylphenyl)propanamide; AC1LEPBR; SCHEMBL1883571; CHEMBL190950; Benzeneacetamide, alpha-methyl-4-(2-methylpropyl)-, (R)-; Benzeneacetamide,alpha-methyl-4-(2-methylpropyl)-,(alphaR)-; ZINC112491; Benzeneacetamide, alpha-methyl-4-(2-methylpropyl)-, (alphaR)-; ZB003774; (R)-alpha-Methyl-4-isobutylbenzeneacetamide; (2R)-2-[4-(2-methylpropyl)phenyl]propanamide; UNII-74M0104F2J component REUQKCDCQVNKLW-SNVBAGLBSA-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C13H19NO
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| Canonical SMILES |
CC(C)CC1=CC=C(C=C1)C(C)C(=O)N
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| InChI |
1S/C13H19NO/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H2,14,15)/t10-/m1/s1
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| InChIKey |
REUQKCDCQVNKLW-SNVBAGLBSA-N
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| CAS Number |
CAS 121839-78-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | C-X-C chemokine receptor type 1 (CXCR1) | Target Info | Inhibitor | [1] |
| C-X-C chemokine receptor type 2 (CXCR2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Chemokine signaling pathway | ||||
| Endocytosis | ||||
| Epithelial cell signaling in Helicobacter pylori infection | ||||
| NetPath Pathway | TNFalpha Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Interleukin signaling pathway | ||||
| Pathway Interaction Database | IL8- and CXCR2-mediated signaling events | |||
| IL8- and CXCR1-mediated signaling events | ||||
| Reactome | Chemokine receptors bind chemokines | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| Differentiation Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors. J Med Chem. 2005 Jun 30;48(13):4312-31. | |||
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