Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06AFD
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| Former ID |
DNC011649
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| Drug Name |
N-Hydroxy-3-naphthalen-2-yl-N-p-tolyl-acrylamide
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| Synonyms |
CHEMBL366714; N-Hydroxy-3-naphthalen-2-yl-N-p-tolyl-acrylamide; BDBM50015103; (E)-3-(2-Naphthalenyl)-N-(4-methylphenyl)-2-propenehydroxamic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H17NO2
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| Canonical SMILES |
CC1=CC=C(C=C1)N(C(=O)C=CC2=CC3=CC=CC=C3C=C2)O
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| InChI |
1S/C20H17NO2/c1-15-6-11-19(12-7-15)21(23)20(22)13-9-16-8-10-17-4-2-3-5-18(17)14-16/h2-14,23H,1H3/b13-9+
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| InChIKey |
MXCQZPFMNOZXSH-UKTHLTGXSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships. J Med Chem. 1990 Mar;33(3):992-8. | |||
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