Drug Information
Drug General Information | Top | |||
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Drug ID |
D06BSV
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Drug Name |
PMID30107136-Compound-Example46
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Drug Type |
Small molecule immunotherapy
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Indication | Hepatitis [ICD-11: DB97.Z] | Patented | [1] | |
Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Patented | [1] | ||
Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] | Patented | [1] | ||
Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
Company |
INCYTE CORPORATION
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Structure |
Download2D MOL |
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Formula |
C22H24N2OS
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Canonical SMILES |
CC1=C(C=CC=C1C2=NC3=C(S2)CN(CC3)CC(C)O)C4=CC=CC=C4
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InChI |
1S/C22H24N2OS/c1-15(25)13-24-12-11-20-21(14-24)26-22(23-20)19-10-6-9-18(16(19)2)17-7-4-3-5-8-17/h3-10,15,25H,11-14H2,1-2H3/t15-/m0/s1
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InChIKey |
HABSDVBVXAIOBF-HNNXBMFYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target Info | Inhibitor | [1] |
Target's Patent Info | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target's Patent Info | [1] |
References | Top | |||
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REF 1 | A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678. |
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