Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06FWC
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| Former ID |
DAP000934
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| Drug Name |
Fludiazepam
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| Synonyms |
Erispan; Fludiazepamum; ID 540; Erispan (TN); Fludiazepam [INN:JAN]; Fludiazepamum [INN-Latin]; ID-540; Fludiazepam (JP15/INN); 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-methyl-(9CI); 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one; 7-Chloro-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-5-(2-fluorophenyl)-1-methyl-1H-1,4-benzodiazepin-2(3H)-one; 7-Chloro-5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one; 7-chloro-5-(2-fluorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one
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| Drug Type |
Small molecular drug
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Approved | [1] | |
| Therapeutic Class |
Antianxiety Agents
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| Company |
Dainippon Sumitomo Pharma
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H12ClFN2O
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| Canonical SMILES |
CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F
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| InChI |
1S/C16H12ClFN2O/c1-20-14-7-6-10(17)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)18/h2-8H,9H2,1H3
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| InChIKey |
ROYOYTLGDLIGBX-UHFFFAOYSA-N
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| CAS Number |
CAS 3900-31-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5329903, 7848417, 8152143, 10521344, 15073015, 22395274, 24775726, 29222504, 46507563, 50068854, 57321758, 58106961, 75208789, 103174587, 104303311, 125536937, 129160840, 134338209, 134984752, 137005587, 160964811, 162946636, 179323228, 196104470, 198979290, 198993235, 221672960, 226520183, 241076737, 250109099
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| ChEBI ID |
CHEBI:31618
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| SuperDrug ATC ID |
N05BA17
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| SuperDrug CAS ID |
cas=003900310
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Fludiazepam, 2008. eduDrugs. | |||
| REF 2 | Benzodiazepines and their metabolites: relationship between binding affinity to the benzodiazepine receptor and pharmacological activity. Life Sci. 1985 Jan 14;36(2):113-9. | |||
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