Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06GRW
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| Former ID |
DNC011698
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| Drug Name |
N-Hydroxy-N-methyl-2,3,3-triphenyl-acrylamide
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| Synonyms |
CHEMBL174161; N-Hydroxy-N-methyl-2,3,3-triphenyl-acrylamide; BDBM50015154; 2,3,3-Triphenyl-N-methyl-2-propenehydroxamic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H19NO2
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| Canonical SMILES |
CN(C(=O)C(=C(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=CC=C3)O
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| InChI |
1S/C22H19NO2/c1-23(25)22(24)21(19-15-9-4-10-16-19)20(17-11-5-2-6-12-17)18-13-7-3-8-14-18/h2-16,25H,1H3
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| InChIKey |
ORTZIDPYVDIVSI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships. J Med Chem. 1990 Mar;33(3):992-8. | |||
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