Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06HLY
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| Former ID |
DAP001113
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| Drug Name |
Pilocarpine
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| Synonyms |
Adsorbocarpine; Almocarpine; Epicar; Isopilocarpine; Isoptocarpine; Miocarpine; Ocusert; Pilagan; Pilocarpin; Pilocarpol; Pilokarpin; Pilokarpol; Pilostat; Salagen; Spersacarpine; Syncarpine; Amistura P; Isopto carpine; Minims Pilocarpine; Ocusert pilo; Pilocarpine HCl; Pilocarpine chloride; Pilocarpine nitrate; Ocusert P 20;Beta-Pilocarpine hydrochloride; Diocarpine (TN); Isopto Carpine (TN); Mi-Pilo; Miocarpine (TN); Ocu-Carpine; Ocusert Pilo-40; Ocusert pilo-20; Pilocarpine (TN); Pilopine HS (TN); Piloptic-1; Piloptic-2; Piloptic-3; Piloptic-4; Piloptic-6; Salagen (TN); Scheinpharm (TN); Timpilo (TN); Ocusert Pilo-20 (TN); Ocusert pilo-20 (TN); P.V. Carpine Liquifilm; Pilocarpine (JAN/USP); Pilocarpine [USAN:BAN:JAN]; Piloptic-1/2; Pilocarpine Mononitrate, (3S-cis)-Isomer; Pilocarpine, Monohydrochloride, (3S-cis)-Isomer; Imidazole-5-butyric acid, alpha-ethyl-beta-(hydroxymethyl)-1-methyl-, gamma-lactone; (+)-Pilocarpine; (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one; (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one; (3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone; (3S-cis)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone; (3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone; 3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)dihydrofuran-2-one; 3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydro-2(3H)-furanone; 3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one; 3-ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydro-2(3H)-furanone; 3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
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| Drug Type |
Small molecular drug
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| Indication | Glaucoma/ocular hypertension [ICD-11: 9C61; ICD-9: 365] | Approved | [1], [2] | |
| Therapeutic Class |
Cholinergic Agents
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| Company |
Alcon Laboratories
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| Structure |
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Download2D MOL |
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| Formula |
C11H16N2O2
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| Canonical SMILES |
CCC1C(COC1=O)CC2=CN=CN2C
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| InChI |
1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
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| InChIKey |
QCHFTSOMWOSFHM-WPRPVWTQSA-N
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| CAS Number |
CAS 92-13-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9677, 605273, 7847591, 7980323, 8153662, 11113352, 11335533, 11360772, 11364001, 11366563, 11369125, 11371791, 11374095, 11377287, 11408793, 11461744, 11466477, 11467597, 11485023, 11486173, 11489100, 11490362, 11492293, 11494921, 11537578, 15195683, 15195684, 25631341, 26697419, 26751548, 29204486, 29224937, 46507475, 47213197, 47291056, 47291057, 47365110, 47440175, 47588917, 47736396, 47885334, 48110373, 48259150, 48414341, 48416432, 49698499, 49857637, 50070744, 50104139, 50104140
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| ChEBI ID |
CHEBI:8207
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| ADReCS Drug ID | BADD_D01771 | |||
| SuperDrug ATC ID |
N07AX01; S01EB01
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| SuperDrug CAS ID |
cas=000092137
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| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 305). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020619. | |||
| REF 3 | Retinoic acid prevents virus-induced airway hyperreactivity and M2 receptor dysfunction via anti-inflammatory and antiviral effects. Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L340-6. | |||
| REF 4 | Muscarinic activation attenuates abnormal processing of beta-amyloid precursor protein induced by cobalt chloride-mimetic hypoxia in retinal gangli... Biochem Biophys Res Commun. 2009 Jun 19;384(1):110-3. | |||
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