Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06JBN
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| Former ID |
DNC013451
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| Drug Name |
2-arachidonoylglycerol
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| Synonyms |
2-arachidonoylglycerol; 2-AG; 2-Arachidonylglycerol; 2-Arachidonyl-glycerol; 53847-30-6; 2-Arachidonoyl-glycerol; 2-Arachidonoyl Glycerol; 2-Ara-Gl; 2-Monoarachidonoylglycerol; UNII-8D239QDW64; 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate; CHEMBL122972; CHEBI:52392; RCRCTBLIHCHWDZ-DOFZRALJSA-N; 8D239QDW64; MG(20:4); MG(0:0/20:4(5Z,8Z,11Z,14Z)/0:0); 5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,8Z,11Z,14Z)-; 5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethy
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C23H38O4
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| Canonical SMILES |
CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC(CO)CO
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| InChI |
1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
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| InChIKey |
RCRCTBLIHCHWDZ-DOFZRALJSA-N
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| CAS Number |
CAS 53847-30-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
854101, 7978582, 8616982, 10587965, 14902345, 24891388, 26683780, 26755008, 26755009, 26755010, 26758249, 39315745, 47216528, 47515072, 47810500, 47959461, 49681165, 49964847, 50110869, 53787325, 56365470, 56464581, 57358604, 58106671, 71855496, 80173887, 85208906, 85292010, 85788015, 91703116, 92309829, 99300743, 99302261, 99368390, 103352217, 104046578, 113856837, 126525112, 134350656, 135065637, 135651394, 137020641, 142472564, 162254924, 163688580, 175270641, 179205535, 184021181, 198979015, 226503932
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| ChEBI ID |
CHEBI:52392
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid amide hydrolase (FAAH) | Target Info | Inhibitor | [2] |
| BioCyc | Anandamide degradation | |||
| KEGG Pathway | Retrograde endocannabinoid signaling | |||
| Panther Pathway | Anandamide degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 729). | |||
| REF 2 | Conformationally constrained analogues of 2-arachidonoylglycerol. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5959-63. | |||
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