Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06ORV
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| Former ID |
DNC009816
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| Drug Name |
Phenethylboronic acid
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| Synonyms |
Phenethylboronic acid; 34420-17-2; 2-phenylethylboronic acid; Phenylethane boronic acid; PEBA; 2-Phenyl-1-ethylboronic acid; Phenylethaneboronic acid; (2-phenylethyl)boronic acid; 2-Phenylethyl-1-boronic acid; Boronic acid, (2-phenylethyl)-; 2-Phenylethyl boronic acid; PHENYLETHYLBORONIC ACID; Phenethylboronicacid; phenethyl boronic acid; PubChem14049; Alkylboronic Acid, 21; ACMC-1AFPT; (2-phenylethyl)boranediol; 2-phenylethane boronic acid; KSC489K8F; SCHEMBL129543; CHEMBL20461; AC1L235V; KS-00000ETI; BDBM26142; CTK3I9582
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H11BO2
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| Canonical SMILES |
B(CCC1=CC=CC=C1)(O)O
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| InChI |
1S/C8H11BO2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-5,10-11H,6-7H2
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| InChIKey |
VPRUMANMDWQMNF-UHFFFAOYSA-N
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| CAS Number |
CAS 34420-17-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase I (CA-I) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] | |
| Fatty acid amide hydrolase (FAAH) | Target Info | Inhibitor | [2] | |
| BioCyc | Anandamide degradation | |||
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| Retrograde endocannabinoid signaling | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Panther Pathway | Anandamide degradation | |||
| Pathwhiz Pathway | Gastric Acid Production | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids. Bioorg Med Chem Lett. 2009 May 15;19(10):2642-5. | |||
| REF 2 | Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. J Med Chem. 2008 Nov 27;51(22):7057-60. | |||
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