Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06UXL
|
|||
| Former ID |
DIB014087
|
|||
| Drug Name |
GI-248573
|
|||
| Indication | Bladder disease [ICD-11: DC11-DC1Z; ICD-10: K80-K87] | Terminated | [1] | |
| Company |
Glaxo Wellcome plc
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholecystokinin receptor type A (CCKAR) | Target Info | Modulator | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Insulin secretion | ||||
| Pancreatic secretion | ||||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008844) | |||
| REF 2 | US patent application no. 8,748,419, Antagonists. | |||
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