Target and Pathway |
Top |
Target(s) |
B-Raf messenger RNA (BRAF mRNA) |
Target Info
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Inhibitor |
[1] |
Glycogen synthase kinase-3 beta (GSK-3B) |
Target Info
|
Inhibitor |
[1] |
LCK tyrosine protein kinase (LCK) |
Target Info
|
Inhibitor |
[1] |
Stress-activated protein kinase 2a (p38 alpha) |
Target Info
|
Inhibitor |
[1] |
Stress-activated protein kinase 2b (p38 beta) |
Target Info
|
Inhibitor |
[1] |
KEGG Pathway
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MAPK signaling pathway
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Rap1 signaling pathway
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FoxO signaling pathway
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Sphingolipid signaling pathway
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Adrenergic signaling in cardiomyocytes
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VEGF signaling pathway
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Osteoclast differentiation
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Signaling pathways regulating pluripotency of stem cells
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Platelet activation
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Toll-like receptor signaling pathway
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NOD-like receptor signaling pathway
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RIG-I-like receptor signaling pathway
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T cell receptor signaling pathway
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Fc epsilon RI signaling pathway
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TNF signaling pathway
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Leukocyte transendothelial migration
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Neurotrophin signaling pathway
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Retrograde endocannabinoid signaling
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Dopaminergic synapse
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Inflammatory mediator regulation of TRP channels
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GnRH signaling pathway
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Progesterone-mediated oocyte maturation
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Prolactin signaling pathway
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Amyotrophic lateral sclerosis (ALS)
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Epithelial cell signaling in Helicobacter pylori infection
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Shigellosis
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Salmonella infection
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Pertussis
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Leishmaniasis
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Tuberculosis
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Hepatitis C
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Influenza A
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Epstein-Barr virus infection
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Proteoglycans in cancer
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NF-kappa B signaling pathway
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Natural killer cell mediated cytotoxicity
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HTLV-I infection
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Primary immunodeficiency
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ErbB signaling pathway
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Chemokine signaling pathway
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Cell cycle
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PI3K-Akt signaling pathway
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Wnt signaling pathway
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Hedgehog signaling pathway
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Axon guidance
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Hippo signaling pathway
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Focal adhesion
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B cell receptor signaling pathway
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Insulin signaling pathway
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Melanogenesis
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Thyroid hormone signaling pathway
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Non-alcoholic fatty liver disease (NAFLD)
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Alzheimer's disease
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Measles
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Pathways in cancer
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Colorectal cancer
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Endometrial cancer
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Prostate cancer
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Basal cell carcinoma
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cAMP signaling pathway
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mTOR signaling pathway
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Vascular smooth muscle contraction
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Long-term potentiation
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Serotonergic synapse
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Long-term depression
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Regulation of actin cytoskeleton
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Alcoholism
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Renal cell carcinoma
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Pancreatic cancer
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Glioma
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Thyroid cancer
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Melanoma
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Bladder cancer
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Chronic myeloid leukemia
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Acute myeloid leukemia
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Non-small cell lung cancer
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NetPath Pathway
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IL5 Signaling Pathway
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FSH Signaling Pathway
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TCR Signaling Pathway
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IL2 Signaling Pathway
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IL-7 Signaling Pathway
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Panther Pathway
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Alzheimer disease-amyloid secretase pathway
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Angiogenesis
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B cell activation
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EGF receptor signaling pathway
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FGF signaling pathway
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Interferon-gamma signaling pathway
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Oxidative stress response
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Parkinson disease
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TGF-beta signaling pathway
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Toll receptor signaling pathway
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VEGF signaling pathway
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Ras Pathway
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p53 pathway feedback loops 2
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p38 MAPK pathway
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CCKR signaling map ST
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T cell activation
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Alzheimer disease-presenilin pathway
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Cadherin signaling pathway
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Hedgehog signaling pathway
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Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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Insulin/IGF pathway-protein kinase B signaling cascade
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Interleukin signaling pathway
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PDGF signaling pathway
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PI3 kinase pathway
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Wnt signaling pathway
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Integrin signalling pathway
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Pathwhiz Pathway
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Fc Epsilon Receptor I Signaling in Mast Cells
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Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
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Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
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Pathway Interaction Database
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Endothelins
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BCR signaling pathway
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p73 transcription factor network
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p38 MAPK signaling pathway
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Atypical NF-kappaB pathway
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IL4-mediated signaling events
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CD40/CD40L signaling
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IL12-mediated signaling events
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Regulation of p38-alpha and p38-beta
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CDC42 signaling events
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Angiopoietin receptor Tie2-mediated signaling
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FAS (CD95) signaling pathway
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Thromboxane A2 receptor signaling
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
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Glucocorticoid receptor regulatory network
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IL2-mediated signaling events
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Rapid glucocorticoid signaling
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Regulation of Androgen receptor activity
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ATF-2 transcription factor network
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IL6-mediated signaling events
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p38 signaling mediated by MAPKAP kinases
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Retinoic acid receptors-mediated signaling
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CXCR3-mediated signaling events
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Signaling mediated by p38-alpha and p38-beta
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EPO signaling pathway
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Signaling events mediated by VEGFR1 and VEGFR2
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p53 pathway
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S1P2 pathway
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Trk receptor signaling mediated by the MAPK pathway
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VEGFR3 signaling in lymphatic endothelium
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FGF signaling pathway
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RAC1 signaling pathway
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Regulation of retinoblastoma protein
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Plasma membrane estrogen receptor signaling
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Glypican 1 network
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TCR signaling in naï
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Signaling events mediated by PTP1B
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TCR signaling in naï
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SHP2 signaling
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CXCR4-mediated signaling events
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Class I PI3K signaling events
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IL2 signaling events mediated by PI3K
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amb2 Integrin signaling
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EPHA forward signaling
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PDGFR-beta signaling pathway
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IL2 signaling events mediated by STAT5
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Ephrin B reverse signaling
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Alpha-synuclein signaling
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LPA receptor mediated events
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Degradation of beta catenin
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Reelin signaling pathway
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Presenilin action in Notch and Wnt signaling
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Integrin-linked kinase signaling
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LKB1 signaling events
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Canonical Wnt signaling pathway
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C-MYC pathway
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BMP receptor signaling
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Hedgehog signaling events mediated by Gli proteins
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Signaling events mediated by Stem cell factor receptor (c-Kit)
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Validated transcriptional targets of deltaNp63 isoforms
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Aurora A signaling
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Insulin-mediated glucose transport
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Class I PI3K signaling events mediated by Akt
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Trk receptor signaling mediated by PI3K and PLC-gamma
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mTOR signaling pathway
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Ras signaling in the CD4+ TCR pathway
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ErbB1 downstream signaling
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Reactome
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NOD1/2 Signaling Pathway
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p38MAPK events
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ERK/MAPK targets
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Activation of PPARGC1A (PGC-1alpha) by phosphorylation
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Oxidative Stress Induced Senescence
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CDO in myogenesis
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DSCAM interactions
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ADP signalling through P2Y purinoceptor 1
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Platelet sensitization by LDL
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VEGFA-VEGFR2 Pathway
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activated TAK1 mediates p38 MAPK activation
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Activation of the AP-1 family of transcription factors
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KSRP (KHSRP) binds and destabilizes mRNA
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GPVI-mediated activation cascade
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PIP3 activates AKT signaling
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Regulation of KIT signaling
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Phosphorylation of CD3 and TCR zeta chains
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Translocation of ZAP-70 to Immunological synapse
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Generation of second messenger molecules
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PECAM1 interactions
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Constitutive Signaling by Aberrant PI3K in Cancer
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DAP12 signaling
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CD28 co-stimulation
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CD28 dependent PI3K/Akt signaling
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CD28 dependent Vav1 pathway
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CTLA4 inhibitory signaling
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PD-1 signaling
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Interleukin-2 signaling
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Degradation of beta-catenin by the destruction complex
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AKT phosphorylates targets in the cytosol
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Regulation of HSF1-mediated heat shock response
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CRMPs in Sema3A signaling
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Disassembly of the destruction complex and recruitment of AXIN to the membrane
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S33 mutants of beta-catenin aren't phosphorylated
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S37 mutants of beta-catenin aren't phosphorylated
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S45 mutants of beta-catenin aren't phosphorylated
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T41 mutants of beta-catenin aren't phosphorylated
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Degradation of GLI2 by the proteasome
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Constitutive Signaling by AKT1 E17K in Cancer
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Spry regulation of FGF signaling
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Frs2-mediated activation
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ARMS-mediated activation
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CREB phosphorylation through the activation of Ras
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RAF activation
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MAP2K and MAPK activation
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Negative feedback regulation of MAPK pathway
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Negative regulation of MAPK pathway
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WikiPathways
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Toll-like receptor signaling pathway
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Monoamine Transport
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Serotonin HTR1 Group and FOS Pathway
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TCR Signaling Pathway
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Senescence and Autophagy in Cancer
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Interferon type I signaling pathways
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Insulin Signaling
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EGF/EGFR Signaling Pathway
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MAPK Cascade
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Oxidative Stress
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p38 MAPK Signaling Pathway
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IL-4 Signaling Pathway
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MAPK Signaling Pathway
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TGF beta Signaling Pathway
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Kit receptor signaling pathway
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Cardiac Hypertrophic Response
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MAP kinase activation in TLR cascade
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Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
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Nanoparticle-mediated activation of receptor signaling
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Structural Pathway of Interleukin 1 (IL-1)
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JAK/STAT
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Amyotrophic lateral sclerosis (ALS)
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Alpha 6 Beta 4 signaling pathway
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Cardiac Progenitor Differentiation
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BDNF signaling pathway
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Integrated Pancreatic Cancer Pathway
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Oncostatin M Signaling Pathway
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Parkinsons Disease Pathway
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Corticotropin-releasing hormone
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AGE/RAGE pathway
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B Cell Receptor Signaling Pathway
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Prostate Cancer
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TSLP Signaling Pathway
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TWEAK Signaling Pathway
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FSH signaling pathway
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Leptin signaling pathway
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RANKL/RANK Signaling Pathway
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miR-targeted genes in muscle cell - TarBase
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miR-targeted genes in lymphocytes - TarBase
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miR-targeted genes in leukocytes - TarBase
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miR-targeted genes in epithelium - TarBase
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IL-1 signaling pathway
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Signal amplification
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Platelet homeostasis
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NGF signalling via TRKA from the plasma membrane
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Myogenesis
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DSCAM interactions
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MicroRNAs in cardiomyocyte hypertrophy
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Angiogenesis
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Physiological and Pathological Hypertrophy of the Heart
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Regulation of toll-like receptor signaling pathway
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Notch Signaling Pathway
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IL-2 Signaling Pathway
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Inflammatory Response Pathway
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Signaling by SCF-KIT
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DAP12 interactions
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Host Interactions of HIV factors
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PIP3 activates AKT signaling
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T-Cell Receptor and Co-stimulatory Signaling
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TCR signaling
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Costimulation by the CD28 family
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DNA Damage Response (only ATM dependent)
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Glycogen Metabolism
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Wnt Signaling Pathway
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Wnt Signaling Pathway and Pluripotency
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IL-6 signaling pathway
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Wnt Signaling Pathway Netpath
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Copper homeostasis
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Focal Adhesion
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Hair Follicle Development: Induction (Part 1 of 3)
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Degradation of beta-catenin by the destruction complex
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IL17 signaling pathway
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Neural Crest Differentiation
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Alzheimers Disease
|
IL-7 Signaling Pathway
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Regulation of Microtubule Cytoskeleton
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Semaphorin interactions
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Cell Cycle
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Androgen receptor signaling pathway
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IL-5 Signaling Pathway
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Serotonin Receptor 4/6/7 and NR3C Signaling
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Regulation of Actin Cytoskeleton
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Bladder Cancer
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Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
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Polycystic Kidney Disease Pathway
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Signaling Pathways in Glioblastoma
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Integrated Breast Cancer Pathway
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Signaling by FGFR
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Integrin-mediated Cell Adhesion
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