Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D06ZWQ
|
|||
Former ID |
DNC007577
|
|||
Drug Name |
2-phenyl-2H-pyrazolo[3,4-c]quinolin-4(5H)-one
|
|||
Synonyms |
2-phenyl-2,5-dihydro-4H-pyrazolo[3,4-c]quinolin-4-one; 109740-09-2; CHEMBL241987; 2-phenyl-2H-pyrazolo[3,4-c]quinolin-4(5H)-one; 2-phenyl-2H,4H,5H-pyrazolo[3,4-c]quinolin-4-one; AC1NLR9L; AC1Q6GQQ; 2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one; MLS001176701; SCHEMBL728937; cid_4962866; CTK7H0251; DTXSID10407182; ISMLHIIGSRUCOQ-UHFFFAOYSA-N; MolPort-002-469-503; HMS2920J03; HMS1784C01; ZINC3888482; BDBM50218922; AKOS027391050; NE38059; MCULE-7237346858; SMR000595674; EN300-14160; SR-01000074278; SR-01000074278-1; J-002324
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C16H11N3O
|
|||
Canonical SMILES |
C1=CC=C(C=C1)N2C=C3C4=CC=CC=C4NC(=O)C3=N2
|
|||
InChI |
1S/C16H11N3O/c20-16-15-13(12-8-4-5-9-14(12)17-16)10-19(18-15)11-6-2-1-3-7-11/h1-10H,(H,17,20)
|
|||
InChIKey |
ISMLHIIGSRUCOQ-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 109740-09-2
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
KEGG Pathway | cGMP-PKG signaling pathway | |||
cAMP signaling pathway | ||||
Sphingolipid signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Morphine addiction | ||||
NetPath Pathway | TCR Signaling Pathway | |||
RANKL Signaling Pathway | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Reactome | Adenosine P1 receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Nucleotide GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
---|---|---|---|---|
REF 1 | New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluati... J Med Chem. 2007 Aug 23;50(17):4061-74. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.