Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07ETD
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| Former ID |
DNC013250
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| Drug Name |
N6-(4-hydroxybenzyl)adenine riboside
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| Synonyms |
N6-(4-Hydroxybenzyl)-adenosine; 110505-75-4; n6-(4-hydroxybenzyl)adenosine; N6-(4-hydroxybenzyl)adenine riboside; CHEMBL224024; C17H19N5O5; p-Topolin riboside; Adenosine, N-[(4-hydroxyphenyl)methyl]-; SCHEMBL639446; N6-(p-hydroxybenzyl)-adenosine; KS-00001DDJ; CTK0D4708; DTXSID00440568; UGVIXKXYLBAZND-LSCFUAHRSA-N; MolPort-023-332-931; ZINC28638129; BDBM50208945; 1962AA; ANW-64712; AKOS016007097; CS-5067; NCGC00484059-01; HY-18775; AJ-83558; TC-153457; KB-258567; AB3000026; AX8235067
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H19N5O5
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| Canonical SMILES |
C1=CC(=CC=C1CNC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O)O
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| InChI |
1S/C17H19N5O5/c23-6-11-13(25)14(26)17(27-11)22-8-21-12-15(19-7-20-16(12)22)18-5-9-1-3-10(24)4-2-9/h1-4,7-8,11,13-14,17,23-26H,5-6H2,(H,18,19,20)/t11-,13-,14-,17-/m1/s1
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| InChIKey |
UGVIXKXYLBAZND-LSCFUAHRSA-N
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| CAS Number |
CAS 110505-75-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A2a receptor (ADORA2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Calcium signaling pathway | ||||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Vascular smooth muscle contraction | ||||
| Parkinson's disease | ||||
| Alcoholism | ||||
| Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | |||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| Reactome | NGF-independant TRKA activation | |||
| Adenosine P1 receptors | ||||
| G alpha (s) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Nucleotide GPCRs | |||
| Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| NGF signalling via TRKA from the plasma membrane | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Neuroprotective principles from Gastrodia elata. J Nat Prod. 2007 Apr;70(4):571-4. | |||
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