Drug Information
Drug General Information | Top | |||
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Drug ID |
D07JRW
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Former ID |
DNC009189
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Drug Name |
Jaspic acid
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Synonyms |
(-)-jaspic acid; jaspic acid; CHEMBL180947; (-)-Jaspic acid; BDBM50240937; 4-Hydroxy-3-[(1S,4aS,5R,8aS)-2,5,8a-trimethyl-5-(4-methyl-pent-3-enyl)-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ylmethyl]-benzoic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C27H38O3
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Canonical SMILES |
CC1=CCC2C(CCCC2(C1CC3=C(C=CC(=C3)C(=O)O)O)C)(C)CCC=C(C)C
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InChI |
1S/C27H38O3/c1-18(2)8-6-13-26(4)14-7-15-27(5)22(19(3)9-12-24(26)27)17-21-16-20(25(29)30)10-11-23(21)28/h8-11,16,22,24,28H,6-7,12-15,17H2,1-5H3,(H,29,30)/t22-,24-,26-,27+/m0/s1
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InChIKey |
IIMZFSAVKIVVHG-DAANFHMWSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 12-lipoxygenase (12-LOX) | Target Info | Inhibitor | [1] |
Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] | |
BioCyc | Resolvin D biosynthesis | |||
Lipoxin biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Linoleic acid metabolism | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
Pathway Interaction Database | IL4-mediated signaling events | |||
WikiPathways | Arachidonic acid metabolism | |||
Eicosanoid Synthesis |
References | Top | |||
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REF 1 | Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. J Nat Prod. 2003 Feb;66(2):230-5. |
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