Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07LMI
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| Former ID |
DNC014520
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| Drug Name |
1-Benzyl-2-methyl-1H-imidazole
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| Synonyms |
1-Benzyl-2-methyl-1H-imidazole; 1-Benzyl-2-methylimidazole; 13750-62-4; N-Benzyl-2-methylimidazole; Imidazole, 1-benzyl-2-methyl-; 1H-Imidazole, 2-methyl-1-(phenylmethyl)-; EINECS 237-333-8; 1H-Imidazole, methyl(phenylmethyl)-; 2-methyl-1-benzylimidazole; PubChem9442; ACMC-209ccp; SCHEMBL81625; 1-benzyl-2-methyl imidazole; labotest-bb lt00455538; KSC427M1B; MLS001074953; BDBM7885; AC1Q4X69; AC1L35Z6; CHEMBL1269154; DTXSID4065604; FBHPRUXJQNWTEW-UHFFFAOYSA-N; MolPort-003-931-164; HMS3372N18; ZINC156633; HMS2231D21; SBB058028
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C11H12N2
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| Canonical SMILES |
CC1=NC=CN1CC2=CC=CC=C2
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| InChI |
1S/C11H12N2/c1-10-12-7-8-13(10)9-11-5-3-2-4-6-11/h2-8H,9H2,1H3
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| InChIKey |
FBHPRUXJQNWTEW-UHFFFAOYSA-N
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| CAS Number |
CAS 13750-62-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6495-9. | |||
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