Drug Information
Drug General Information | Top | |||
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Drug ID |
D07MYE
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Former ID |
DNC011715
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Drug Name |
N-Hydroxy-3-phenyl-acrylamide
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Synonyms |
Cinnamoylhydroxamic acid; CINNAMOHYDROXAMIC ACID; Hydroxylamine, N-cinnamoyl-; 2-Propenamide, N-hydroxy-3-phenyl-; N-Hydroxycinnamamide; UNII-434STJ4H11; N-Hydroxy-3-phenyl-2-propenamide; NSC 42128; NSC-42128; NSC-44617; NSC 44617; CHEMBL154574; 3669-32-7; 434STJ4H11; WLN: QMV1U1R; N-Hydroxy-3-phenyl-acrylamide; Cinnamohydroxamic acid, (E)-; Cinnamoylhydroxamic acid [INCI]; MAZ 1704; MAZ-1704; 2-Propenamide, N-hydroxy-3-phenyl-, (E)-; 2-Propenamide, N-hydroxy-3-phenyl-, (2E)-; AC1Q5CS7; AC1NS7U4; SCHEMBL559917
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C9H9NO2
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Canonical SMILES |
C1=CC=C(C=C1)C=CC(=O)NO
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InChI |
1S/C9H9NO2/c11-9(10-12)7-6-8-4-2-1-3-5-8/h1-7,12H,(H,10,11)/b7-6+
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InChIKey |
UVDDFTZLVFIQFL-VOTSOKGWSA-N
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CAS Number |
CAS 3669-32-7
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
Resolvin D biosynthesis | ||||
Leukotriene biosynthesis | ||||
Lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | ||||
Aspirin triggered resolvin E biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Ovarian steroidogenesis | ||||
Toxoplasmosis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Vitamin D Receptor Pathway | |||
Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships. J Med Chem. 1990 Mar;33(3):992-8. |
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