Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07PYV
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| Former ID |
DNC008849
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| Drug Name |
2-aminopyridine
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| Synonyms |
2-AMINOPYRIDINE; 504-29-0; pyridin-2-amine; 2-Pyridinamine; 2-Pyridylamine; Aminopyridine; Pyridinamine; o-Aminopyridine; 2-aminopyridin; 2-Aminopryidine; Amino-2 pyridine; Pyridine, 2-amino-; 1,2-Dihydro-2-iminopyridine; alpha-Pyridylamine; alpha-Pyridinamine; 2-Pyridinylnitrene; alpha-Aminopyridine; Pyridin-2-ylamine; NSC 431; UNII-WSX981HEWU; 2-pyridinylamine; 2-amino pyridine; Pyridine, amino-; pyridin-2-yl-amine; .beta.-Pyridylamine; .alpha.-Pyridylamine; .alpha.-Pyridinamine; CCRIS 4747; .alpha.-Aminopyridine; 26445-05-6; HSDB 206
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C5H6N2
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| Canonical SMILES |
C1=CC=NC(=C1)N
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| InChI |
1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)
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| InChIKey |
ICSNLGPSRYBMBD-UHFFFAOYSA-N
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| CAS Number |
CAS 504-29-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors. J Med Chem. 2009 Jul 23;52(14):4533-7. | |||
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