Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08NDV
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| Former ID |
DNC013303
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| Drug Name |
4-(1H-indol-3-yl)-1-morpholinobutan-1-one
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| Synonyms |
CHEMBL395709; 4-(1H-indol-3-yl)-1-(morpholin-4-yl)butan-1-one; AC1LDAKL; 4-(1H-indol-3-yl)-1-morpholinobutan-1-one; Oprea1_287687; MLS000073378; SCHEMBL14882056; MolPort-001-888-170; ZINC280650; HMS2314G24; BDBM50207035; STK110153; AKOS000614077; MCULE-8725603794; SMR000013452; 313532-54-6; ST50900693; 4-indol-3-yl-1-morpholin-4-ylbutan-1-one; 4-(1H-indol-3-yl)-1-morpholin-4-ylbutan-1-one; SR-01000362492; 4-(1H-Indol-3-yl)-1-morpholin-4-yl-butan-1-one; SR-01000362492-1
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H20N2O2
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| Canonical SMILES |
C1COCCN1C(=O)CCCC2=CNC3=CC=CC=C32
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| InChI |
1S/C16H20N2O2/c19-16(18-8-10-20-11-9-18)7-3-4-13-12-17-15-6-2-1-5-14(13)15/h1-2,5-6,12,17H,3-4,7-11H2
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| InChIKey |
YFXYLXOHDNYDNC-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Indole derivatives as potent inhibitors of 5-lipoxygenase: design, synthesis, biological evaluation, and molecular modeling. Bioorg Med Chem Lett. 2007 May 1;17(9):2414-20. | |||
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