Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08XFV
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| Former ID |
DAP000242
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| Drug Name |
Flurazepam
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| Synonyms |
Dalmadorm; Dalmane; Felison; Felmane; Flunox; Flurazepamum; Insumin; Noctosom; Paxane; Somnol; Stauroderm; Valdorm; Flurazepam HCL; Flurazepam hydrochloride; Dalmadorm (TN); Dalmane (TN); Dalmane-R; Flurazepamum [INN-Latin]; Insumin (TN); Flurazepam (JP15/INN); Flurazepam [INN:BAN:JAN]; Ro-5-6901/3; 2H-1,4-Benzodiazepin-2-one,7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-, dihydrochloride; 7-Chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1H-1,4-benzodiazepin-2(3H)-one; 7-Chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-chloro-1-(2-diethylaminoethyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one
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| Drug Type |
Small molecular drug
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| Indication | Insomnia [ICD-11: 7A00-7A0Z] | Approved | [1], [2] | |
| Therapeutic Class |
Hypnotics and Sedatives
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| Company |
West-ward Pharmaceutical Corp
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| Structure |
 |
Download2D MOL |
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| Formula |
C21H23ClFN3O
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| Canonical SMILES |
CCN(CC)CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F
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| InChI |
1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3
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| InChIKey |
SAADBVWGJQAEFS-UHFFFAOYSA-N
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| CAS Number |
CAS 17617-23-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5373981, 7847395, 7979292, 8152162, 10510931, 16847426, 26757995, 29222528, 46508451, 48416030, 49884134, 57321773, 74737372, 81065483, 103252248, 104303383, 125343184, 126666911, 127346536, 127346537, 129206359, 131302560, 134337556, 134961907, 134991466, 137005121, 139650929, 144205754, 152029390, 152146193, 160964035, 164814237, 170465018, 175265966, 177513104, 178103763, 179116700, 198993237, 221672978, 223661920, 226416782, 249949893, 252349925
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| ChEBI ID |
CHEBI:5128
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| ADReCS Drug ID | BADD_D00939 ; BADD_D00940 | |||
| SuperDrug ATC ID |
N05CD01
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| SuperDrug CAS ID |
cas=017617231
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Modulator | [3] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7188). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 070344. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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