Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08ZRA
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| Former ID |
DNC012758
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| Drug Name |
C-Naphthalen-1-yl-methylamine
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| Synonyms |
1-Naphthalenemethylamine; 118-31-0; naphthalen-1-ylmethanamine; 1-Naphthylmethylamine; 1-NAPHTHALENEMETHANAMINE; 1-(Aminomethyl)naphthalene; 1-Naphthalenemethyl amine; C-Naphthalen-1-yl-methylamine; 1-Naphthylmethanamine; (1-naphthylmethyl)amine hydrochloride; CHEMBL128633; 1-AMINOMETHYLNAPHTHALENE; naphthylmethylamine; NVSYANRBXPURRQ-UHFFFAOYSA-N; MFCD00004048; 1-Naphthalenemethylamine, 97%; Naphthalene-1-methylamine; naphtalenemethylamine; EINECS 204-244-0; naphth-1-ylmethylamine; 1-naphthylmethyl-amine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H11N
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| Canonical SMILES |
C1=CC=C2C(=C1)C=CC=C2CN
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| InChI |
1S/C11H11N/c12-8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8,12H2
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| InChIKey |
NVSYANRBXPURRQ-UHFFFAOYSA-N
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| CAS Number |
CAS 118-31-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-2A (ADRA2A) | Target Info | Inhibitor | [1] |
| Adrenergic receptor alpha-2B (ADRA2B) | Target Info | Inhibitor | [1] | |
| Adrenergic receptor alpha-2C (ADRA2C) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Reactome | Adrenoceptors | |||
| Adrenaline signalling through Alpha-2 adrenergic receptor | ||||
| Adrenaline,noradrenaline inhibits insulin secretion | ||||
| G alpha (i) signalling events | ||||
| G alpha (z) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Monoamine GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Platelet Aggregation (Plug Formation) | ||||
| Integration of energy metabolism | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Examination of the role of the acidic hydrogen in imparting selectivity of 7-(aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK&F 29661) toward inh... J Med Chem. 1997 Dec 5;40(25):3997-4005. | |||
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