Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09AFJ
|
|||
| Former ID |
DIB016340
|
|||
| Drug Name |
SR-121787
|
|||
| Synonyms |
SR-121566; SR-121566a
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Discontinued in Phase 2 | [1] | |
| Company |
Sanofi-Synthelabo
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C27H37N5O6S
|
|||
| Canonical SMILES |
CCOC(=O)CCN(C1CCN(CC1)CC(=O)OCC)C2=NC(=CS2)C3=CC=C(C=C3)C(=NC(=O)OCC)N
|
|||
| InChI |
1S/C27H37N5O6S/c1-4-36-23(33)13-16-32(21-11-14-31(15-12-21)17-24(34)37-5-2)26-29-22(18-39-26)19-7-9-20(10-8-19)25(28)30-27(35)38-6-3/h7-10,18,21H,4-6,11-17H2,1-3H3,(H2,28,30,35)
|
|||
| InChIKey |
WJMRSKGCJGOLKV-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009197) | |||
| REF 2 | Prevention of thrombosis and enhancement of thrombolysis in rabbits by SR 121787, a glycoprotein II/III antagonist. J Pharmacol Exp Ther. 1998 Aug;286(2):670-5. | |||
| REF 3 | The antithrombotic efficacy of the GP IIb/IIIa antagonist SR121787 is potentiated by antithrombin-dependent factor Xa inhibition without an increas... J Cardiovasc Pharmacol. 1999 Apr;33(4):573-9. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.