Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D09KRA
|
|||
Former ID |
DIB018172
|
|||
Drug Name |
[125I]SCH23982
|
|||
Synonyms |
[125I]-SCH23982
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
|
|||
Formula |
C17H18INO
|
|||
Canonical SMILES |
CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)I
|
|||
InChI |
1S/C17H18INO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1/i18-2
|
|||
InChIKey |
JGBTWNOVLISURM-QFLNOARHSA-N
|
|||
CAS Number |
CAS 116780-39-3
|
|||
PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Dopamine D1 receptor (D1R) | Target Info | Antagonist | [2] |
Dopamine D5 receptor (D5R) | Target Info | Antagonist | [3] | |
KEGG Pathway | Calcium signaling pathway | |||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Dopaminergic synapse | ||||
Parkinson's disease | ||||
Cocaine addiction | ||||
Amphetamine addiction | ||||
Morphine addiction | ||||
Alcoholism | ||||
Panther Pathway | Dopamine receptor mediated signaling pathway | |||
Pathwhiz Pathway | Dopamine Activation of Neurological Reward System | |||
Reactome | Dopamine receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Hypothetical Network for Drug Addiction | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Genes and (Common) Pathways Underlying Drug Addiction | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
---|---|---|---|---|
REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 945). | |||
REF 2 | Molecular cloning and expression of the gene for a human D1 dopamine receptor. Nature. 1990 Sep 6;347(6288):72-6. | |||
REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 218). |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.