Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09PUL
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| Former ID |
DAP000805
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| Drug Name |
L-Alanine
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| Synonyms |
ALA; Alaninum; LPG; Polyalanine; A-Alanine; A-Aminopropionic acid; Alanina [DCIT,Spanish]; Alanine (USP); L-A-Aminopropionicacid; L-Alanine (9CI); L-Alanine (JAN); L-Alanine, homopolymer; L-Alanine, labeled with tritium; L-a-Alanine; L-a-Aminopropionic acid; Poly-DL-alanine; L-Alanine, labeled with carbon-14; Alanine, L-(7CI,8CI); F4F207FF-8FF8-4789-99A1-147AE0A36673; L-Alanine, N-coco alkyl derivs.; Propanoic acid, 2-amino-, (S); (C14)L-Alanine; (S)-2-Aminopropionic acid; 14C-L-Alanine
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| Drug Type |
Small molecular drug
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| Indication | Dietary shortage [ICD-11: 5B5K; ICD-10: E61.9] | Approved | [1], [2], [3] | |
| Glioma [ICD-11: 2A00.0] | Approved | [1], [2], [3] | ||
| Therapeutic Class |
Dietary supplement
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| Structure |
 |
Download2D MOL |
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| Formula |
C3H7NO2
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| Canonical SMILES |
CC(C(=O)O)N
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| InChI |
1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
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| InChIKey |
QNAYBMKLOCPYGJ-REOHCLBHSA-N
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| CAS Number |
CAS 56-41-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3343, 585842, 589753, 627087, 822335, 841591, 3131856, 6436532, 7847080, 7885836, 7888688, 8144737, 8153694, 10527484, 11113404, 11528607, 14710664, 14720011, 14747373, 24845820, 24890849, 24891241, 24891260, 24901893, 29224973, 46504866, 46508779, 49655376, 56437668, 57323073, 57580857, 78123937, 85164877, 85230829, 85239779, 87350317, 87561861, 92297527, 92719579, 96100165, 96100173, 99224270, 99246016, 103059020, 103059733, 103182286, 103827139, 103914796, 104234104, 104310701
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| ChEBI ID |
CHEBI:16977
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA transaminase (ABAT) | Target Info | Inhibitor | [4] |
| BioCyc | GABA shunt | |||
| Valine degradation | ||||
| Beta-alanine degradation | ||||
| 4-aminobutyrate degradation | ||||
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Valine, leucine and isoleucine degradation | ||||
| beta-Alanine metabolism | ||||
| Propanoate metabolism | ||||
| Butanoate metabolism | ||||
| Metabolic pathways | ||||
| GABAergic synapse | ||||
| Panther Pathway | Aminobutyrate degradation | |||
| Pyrimidine Metabolism | ||||
| Gamma-aminobutyric acid synthesis | ||||
| Pathwhiz Pathway | Aspartate Metabolism | |||
| Glutamate Metabolism | ||||
| Beta-Alanine Metabolism | ||||
| Valine, Leucine and Isoleucine Degradation | ||||
| Propanoate Metabolism | ||||
| WikiPathways | GABA synthesis, release, reuptake and degradation | |||
| Alanine and aspartate metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 720). | |||
| REF 2 | Drug information of L-Alanine, Health Canada, 2008. (drugid: 7638) | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. | |||
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