Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09VSK
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| Former ID |
DNC005672
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| Drug Name |
4-(1H-Indol-3-ylmethyl)-phenylamine
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| Synonyms |
Benzenamine, 4-(1H-indol-3-ylmethyl)-; CHEMBL364248; 134627-70-6; 4-(1H-indol-3-ylmethyl)aniline; ACMC-20mvfl; 4-(1H-Indol-3-ylmethyl)-phenylamine; AC1N7FQI; SCHEMBL4224120; CTK0F4358; DTXSID30401708; 4-[(1H-Indol-3-yl)methyl]aniline; BDBM50164747
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H14N2
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=CN2)CC3=CC=C(C=C3)N
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| InChI |
1S/C15H14N2/c16-13-7-5-11(6-8-13)9-12-10-17-15-4-2-1-3-14(12)15/h1-8,10,17H,9,16H2
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| InChIKey |
KDXYOBVEKNURNB-UHFFFAOYSA-N
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| CAS Number |
CAS 134627-70-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 6 receptor (HTR6) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | |||
| Reactome | Serotonin receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Binding of isotryptamines and indenes at h5-HT6 serotonin receptors. Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91. | |||
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