Drug Information
Drug General Information | Top | |||
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Drug ID |
D09WKT
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Former ID |
DIB005726
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Drug Name |
ARD-412
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Synonyms |
Oral delta opioid agonists (premature ejaculation); Oral delta opioid agonists (premature ejaculation), Enhance
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Indication | Premature ejaculation [ICD-11: HA03.0Z; ICD-10: F52.4; ICD-9: 302.75] | Investigative | [1] | |
Company |
Ardent Pharmaceuticals Inc
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Target and Pathway | Top | |||
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Target(s) | Opioid receptor delta (OPRD1) | Target Info | Agonist | [1] |
KEGG Pathway | cGMP-PKG signaling pathway | |||
Sphingolipid signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Enkephalin release | ||||
Opioid proenkephalin pathway | ||||
Opioid proopiomelanocortin pathway | ||||
Reactome | Peptide ligand-binding receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Peptide GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 317). |
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