Drug Information
Drug General Information | Top | |||
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Drug ID |
D09YVA
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Former ID |
DNC012228
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Drug Name |
8-Methoxy-2-(4-methyl-piperazin-1-yl)-quinoline
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Synonyms |
CHEMBL80775; 8-Methoxy-N-methylquipazine; 8-Methoxy-2-(4-methyl-piperazin-1-yl)-quinoline; BDBM50025469
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H19N3O
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Canonical SMILES |
CN1CCN(CC1)C2=NC3=C(C=CC=C3OC)C=C2
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InChI |
1S/C15H19N3O/c1-17-8-10-18(11-9-17)14-7-6-12-4-3-5-13(19-2)15(12)16-14/h3-7H,8-11H2,1-2H3
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InChIKey |
XPBCUYLZAWCBJJ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] | |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Calcium signaling pathway | ||||
Gap junction | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT1 type receptor mediated signaling pathway | ||||
5HT2 type receptor mediated signaling pathway | ||||
Reactome | Serotonin receptors | |||
G alpha (i) signalling events | ||||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Serotonin Receptor 2 and STAT3 Signaling | ||||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | 5-HT1 and 5-HT2 binding characteristics of some quipazine analogues. J Med Chem. 1986 Nov;29(11):2375-80. |
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