Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A6RU
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| Former ID |
DNC013438
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| Drug Name |
7-chloro-1H-indazole
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| Synonyms |
7-chloro-1H-indazole; 37435-12-4; 7-Chloroindazole; 1H-Indazole, 7-chloro-; CHEMBL247367; AK-24465; 7-chlor-1H-indazol; ACMC-1AG86; SCHEMBL104360; SCHEMBL19152469; CTK1C1806; DTXSID80455690; WIYOYUQVNPTVQG-UHFFFAOYSA-N; MolPort-001-767-757; 7-Chloro-1H-indazole, AldrichCPR; ZX-AT002536; BCP27378; BDBM50209244; ZINC12336533; STL554161; SBB054730; MFCD07368214; ANW-28635; OR3680; FCH921470; BBL100367; AKOS024124979; AKOS005072025; VI20076; RP01758; MCULE-5657266195; CB-0833; PB17411; ACM37435124; KB-46237; SC-27673; QC-11238; BL000561; AN-17144
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C7H5ClN2
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| Canonical SMILES |
C1=CC2=C(C(=C1)Cl)NN=C2
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| InChI |
1S/C7H5ClN2/c8-6-3-1-2-5-4-9-10-7(5)6/h1-4H,(H,9,10)
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| InChIKey |
WIYOYUQVNPTVQG-UHFFFAOYSA-N
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| CAS Number |
CAS 37435-12-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. | |||
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