Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A8NB
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| Former ID |
DNC000477
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| Drug Name |
CP-94,253
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| Synonyms |
CP-94253; CP-94,253; Tocris-1317; NCGC00025108-01; AC1N1FU8; SCHEMBL9695044; GTPL3221; CHEMBL1570196; CHEBI:92591; ZINC1894220; BCP28082; AKOS022184337; CP94253; CP94253NIEaNI/CP94253NIEaNI; AJ-32224; LS-139500; L003950; BRD-K33860217-003-01-6; 4-{5-propoxypyrrolo[3,2-b]pyridin-3-yl}-1,2,3,6-tetrahydropyridine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H19N3O
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| Canonical SMILES |
CCCOC1=NC2=C(C=C1)NC=C2C3=CCNCC3
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| InChI |
1S/C15H19N3O/c1-2-9-19-14-4-3-13-15(18-14)12(10-17-13)11-5-7-16-8-6-11/h3-5,10,16-17H,2,6-9H2,1H3
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| InChIKey |
KWQWBZIGHIOKIO-UHFFFAOYSA-N
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| CAS Number |
CAS 131084-35-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:92591
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1B receptor (HTR1B) | Target Info | Agonist | [2] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3221). | |||
| REF 2 | Anxiogenic-like effect of serotonin(1B) receptor stimulation in the rat elevated plus-maze. Pharmacol Biochem Behav. 2002 Apr;71(4):581-7. | |||
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