Drug Information
Drug General Information | Top | |||
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Drug ID |
D0A9ED
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Former ID |
DNC000387
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Drug Name |
Carazolol
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Synonyms |
Carazolol; 57775-29-8; Conducton; Suacron; corazolol; Carazolol [INN:BAN]; 1-((9H-Carbazol-4-yl)oxy)-3-(isopropylamino)propan-2-ol; Carazololum [INN-Latin]; CCRIS 1047; Conducton hydrochloride; 1-(Carbazol-4-yloxy)-3-(isopropylamino)-2-propanol; 1-(9H-carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol; EINECS 260-945-1; BRN 3620576; BM-51052; BM 51052; CHEMBL324665; 1-(9H-carbazol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol; 1-(4-Carbazolyloxy)-3-isopropylamino-2-propanol
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H22N2O2
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Canonical SMILES |
CC(C)NCC(COC1=CC=CC2=C1C3=CC=CC=C3N2)O
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InChI |
1S/C18H22N2O2/c1-12(2)19-10-13(21)11-22-17-9-5-8-16-18(17)14-6-3-4-7-15(14)20-16/h3-9,12-13,19-21H,10-11H2,1-2H3
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InChIKey |
BQXQGZPYHWWCEB-UHFFFAOYSA-N
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CAS Number |
CAS 57775-29-8
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PubChem Compound ID | ||||
PubChem Substance ID |
6685022, 7978853, 8194800, 15468496, 43128022, 50022846, 51091918, 57318337, 79557571, 85208998, 91611495, 103089481, 103153519, 103331481, 103937132, 104351190, 117613301, 126671688, 127555400, 134339829, 135029386, 135650054, 136161295, 137024393, 137251459, 162185417, 162251286, 162863557, 164786782, 172089152, 179150703, 184545382, 206246514, 223674687, 223704591, 226457254, 226457255, 250061443, 251890234, 252359210, 252390123
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ChEBI ID |
CHEBI:135261
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Target and Pathway | Top | |||
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Target(s) | Adrenergic receptor beta-1 (ADRB1) | Target Info | Agonist | [2] |
Adrenergic receptor beta-3 (ADRB3) | Target Info | Agonist | [2] | |
KEGG Pathway | Calcium signaling pathway | |||
cGMP-PKG signaling pathway | ||||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Endocytosis | ||||
Adrenergic signaling in cardiomyocytes | ||||
Gap junction | ||||
Salivary secretion | ||||
Dilated cardiomyopathy | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Beta1 adrenergic receptor signaling pathway | ||||
Beta3 adrenergic receptor signaling pathway | ||||
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | Adrenoceptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
Calcium Regulation in the Cardiac Cell | ||||
GPCRs, Class A Rhodopsin-like | ||||
Endothelin Pathways | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 569). | |||
REF 2 | Current therapeutic uses and potential of beta-adrenoceptor agonists and antagonists. Eur J Clin Pharmacol. 1998 Feb;53(6):389-404. |
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