Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0B2JC
|
|||
Former ID |
DNC010338
|
|||
Drug Name |
[(3-Bromophenyl)-p-tolyl-ketone]thiosemicarbazone
|
|||
Synonyms |
CHEMBL590497; [(3-Bromophenyl)-p-tolyl-ketone]thiosemicarbazone
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C15H14BrN3S
|
|||
Canonical SMILES |
CC1=CC=C(C=C1)C(=NNC(=S)N)C2=CC(=CC=C2)Br
|
|||
InChI |
1S/C15H14BrN3S/c1-10-5-7-11(8-6-10)14(18-19-15(17)20)12-3-2-4-13(16)9-12/h2-9H,1H3,(H3,17,19,20)/b18-14+
|
|||
InChIKey |
IOXFIFMULNCUSH-NBVRZTHBSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Cathepsin B (CTSB) | Target Info | Inhibitor | [1] |
Cathepsin L (CTSL) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Lysosome | |||
Phagosome | ||||
Antigen processing and presentation | ||||
Proteoglycans in cancer | ||||
Rheumatoid arthritis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
TGF_beta_Receptor Signaling Pathway | ||||
TCR Signaling Pathway | ||||
IL2 Signaling Pathway | ||||
Reactome | Endosomal/Vacuolar pathway | |||
Collagen degradation | ||||
Degradation of the extracellular matrix | ||||
Trafficking and processing of endosomal TLR | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
MHC class II antigen presentation | ||||
WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS |
References | Top | |||
---|---|---|---|---|
REF 1 | Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1415-9. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.